Neurotransmission

A neuron generates and propagates an action potential along its axon, then transmits this signal across a synapse by releasing neurotransmitters, which trigger a reaction in another neuron or an effector cell (eg, muscle cells, most exocrine and endocrine cells). The signal may stimulate or inhibit the receiving cell, depending on the neurotransmitter and receptor involved.

In the CNS, interconnections are complex. An impulse from one neuron to another may pass from axon to cell body, axon to dendrite (a neuron’s receiving branches), cell body to cell body, or dendrite to dendrite. A neuron can simultaneously Continue reading “Neurotransmission”

The Brain: Gabapentin (Neurontin)

Well “they” named this DRUG correctly. “Neuro-rotten”.  Gabapentin marketed under the name Neurontin initially as an anti-seizure medicine and was first approved in 1993.

Serious side-effects DO INCLUDE increased risk of suicide, aggressive behavior reduce mental or cognitive ability including memory.   During the onset attempting to gain market share and wide spread acceptance Park-Davis a sub-company of Pfizer used a number of, in my opinion, questionable techniques to encourage doctors to push the drug for disorders not approved for use.

Drug Dealers Of America

Drug dealers bribing Profession Health Care Providers to sell more drugs lead to multiple lawsuits by patience who were harmed and ultimately where settled with multi-million dollar “go away” settlements and millions of dollars in “pay us” fines,  before you pay us  and let us approve it for first fees.

In 2010 the American Headache Society (AHS) and American Academy of Neurology (AAN) guidelines classify gabapentin as a drug with “insufficient data to support or refute use for migraine prophylaxis.“[1] Furthermore, a 2013 Cochrane review concluded that gabapentin was not useful for the prevention of episodic migraine in adults.*[2].

Gabapentin uses the brains GABA pathways to gain access to the synopitic  clef and affect neurotransmission. Please Continue reading “The Brain: Gabapentin (Neurontin)”